Management and optimization of energy consumption has been importantly considered by policy-makers in the field of energy and environment from the perspective of energy security and environmental considerations. In this study, nondominated sorting genetic algorithm (NSGAII) was applied to determine the optimal share of fossil energy sources for energy intensive industries of Iran including The Manufacture of food products and beverages, The Manufacture of coke, refined petroleum products and nuclear fuel, The Manufacture of chemicals and chemical products, The Manufacture of other non-metallic mineral products and The Manufacture of basic metals. According to which the share of kerosene, 0.098%, 0.17%, 0.016%, 0.05%, 0.014%, the share of diesel, 12.88%, 0.93%, 0.62%, 1.97%, 0. 96%, the share of natural gas, 68.81%, 85.25%, 98.29%, 80.32%, 98%, the share of liquefied gas, 0.18%, 2.17%, 0.08%, 2.66%, 0.33%, the share of gasoline, 1.32%, 0.29%, 0.37%, 0.15%, 0.052% and the share of heavy fuel oil 16.7%, 11.18%, 0.62%, 14.83% , 0.65%, was obtained respectively. Then, the study utilized data envelopment analysis (Slack-Based measures) to measure the environmental and economic efficiency in some selected sub-sectors of industry by means of optimal amounts and then compared the results with the real amounts of energy consumption during 2011, 2014, 2015, and 2016. The results of optimization model compared with the real share of energy consumption that indicates the improvement of economic and environmental efficiency in the years under review.